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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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Cialis (Tadalafil) and Other Drug-Food Interactions:

Ketoconazole, which is used to manage fungal infection, may interact with tadalafil. This may affect its blood pressure by increasing the generation of blood clots, leading to symptoms like dizziness or dizziness, a condition known as priapism. Symptoms of combined medications can include:

  • Weight gain
  • High blood pressure
  • Stomach pain
  • Dizziness
  • Diarrhea

3.ravel (a fruit-containing medication) and Alprostadil (e.g., pemoxonidine) can both impact blood pressure. While they do not have the same side effects, both can cause discomfort, especially during sexual activity.

Cialis and Alprostadil are prescription medications used to manage erectile dysfunction (ED). These medications work by relaxing the muscles in the walls of blood vessels, allowing for increased blood flow, which helps achieve and maintain an erection.

Erectile Dysfunction

Erection problems (impotence) are very common, particularly in men over 40.

Most men occasionally fail to get or keep an erection. This is usually due to stress, tiredness, anxiety or drinking too much alcohol, and it’s nothing to worry about.

If it happens more often, it may be caused by physical or emotional problems.

Physical causes Possible cause Treatment Narrowing of penis blood vessels, high blood pressure, high cholesterol medicine to lower blood pressure, statins to lower cholesterol Hormone problems hormone replacement – for example, testosterone Side effects of prescribed medication change to medicine following discussion with GP You may also be asked to make lifestyle changes.

Do lose weight if you’re overweight stop smoking eat a healthy diet exercise daily try to reduce stress and anxiety

Don’t cycle for a while (if you cycle more than 3 hours a week) drink more than 14 units of alcohol a week

  • Side Effects

    Possible side effects

    Like all medicines, this medicine can cause side effects, although not everybody gets them. These effects are normally mild to moderate in nature.

    If you experience any of the following side effects stop using the medicine and seek medical help immediately:

    allergic reactions including rashes (frequency uncommon). chest pain – do not use nitrates but seek immediate medical assistance (frequency uncommon). priapism, a prolonged and possibly painful erection after taking CIALIS (frequency rare). If you have such an erection, which lasts continuously for more than 4 hours you should contact a doctor immediately. sudden loss of vision (frequency rare). Other side effects have been reported:

    Common (seen in 1 to 10 in every 100 patients)

    headache, back pain, muscle aches, pain in arms and legs, facial flushing, nasal congestion, and indigestion. Uncommon (seen in 1 to 10 in every 1,000 patients)

    dizziness, stomach ache, feeling sick, being sick (vomiting), reflux, blurred vision, eye pain, difficulty in breathing, presence of blood in urine, prolonged erection, pounding heartbeat sensation, a fast heart rate, high blood pressure, low blood pressure, nose bleeds, ringing in the ears, swelling of the hands, feet or ankles and feeling tired. Rare (seen in 1 to 10 in every 10,000 patients)

    fainting, seizures and passing memory loss, swelling of the eyelids, red eyes, sudden decrease or loss of hearing, hives (itchy red welts on the surface of the skin), penile bleeding, presence of blood in semen and increased sweating. Heart attack and stroke have also been reported rarely in men taking CIALIS. Most of these men had known heart problems before taking this medicine.

    Partial, temporary, or permanent decrease or loss of vision in one or both eyes has been rarely reported.

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    Other side effects

    The above is not a complete list of side effects. Some other medicines may also potentially cause common side effects.

    If you have any potential side effects not listed, please let ushat block the medicine (see the section ").

    We are not medical experts on medicalities nor do we believe that everyone will have them. We are justolated to have done some basic medical checks. We do not know whether any of your medications met the same criteria as your others. We are headquartered in the UK.

    DISCLAIMER: This is a doctors prescription only medicine, it may differ from usual medicines on the market. It is only for you. Always consult your doctor before starting any medicine or service for which it is not licensed. It is not approved for sexual use. It is not intended as a substitute for professional medical advice, diagnosis or treatment. This contents is not a complete list of the listed medicinal ingredients. If you have questions about the drugs listed or the main ingredient difference between your own NHS-licensed and NHS-generic medicine please talk to your doctor.

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    Please note: There is a difference between a and a with every medicine. In the past doctors might have recommended to you based on whether the problem was related to problems with your health or other factors.

    If you have any concerns about your medicine or problems please speak to your doctor.

    A list of all medicines on the left side of the page alongside all medicines prescribed by the doctors.

    Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

    Common side effects reported from Cialis use include:

    • Headache
    • Indigestion
    • Heartburn
    • Upset stomach
    • Gas
    • Nausea
    • Flushing

    More severe side effects include:

    • Painful erections or erections that last longer than 4 hours
    • Sudden loss of vision
    • Sudden loss of hearing
    • Ringing in the ears
    • Chest pain
    • Shortness of breath
    • Painful urination
    • Increased urination frequency
    • Fainting
    • Dizziness
    • Skin rash
    • Hives
    • Facial swelling

    If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

    As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

    Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

    In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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    This medication can cause serious side effects, including:

    • Allergic reactions to the medication
    • Sudden vomiting
    • Heart attack
    • Heart failure

    As with all prescription medications, inform your doctor if you experience any of the following side effects, which may or may not include side effects:

    • Edema
    • Liver problems
    • Seizures
    • Muscle pain
    • Pain in the chest or pelvic region

    As with all prescription medications, inform your doctor if you experience any of the following side effects, which may or may not include effects on heartbeat or heartbeat-Quickly inform your doctor if you experience any of the following:

    • Permanent changes in vision
    • Permanent changes in hearing
    • Sudden numbness or weakness
    • Sudden vision loss
    • Sudden chest pain
    • Sudden vision problems
    • Sudden hearing decrease

    As with all prescription medications, inform your doctor if you experience any of the following side effects, which may not be listed on the product specifications.

    Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

    Common side effects reported from Cialis use include:

    • Headache
    • Indigestion
    • Heartburn
    • Upset stomach
    • Gas
    • Nausea
    • Flushing

    More severe side effects include:

    • Painful erections or erections that last longer than 4 hours
    • Sudden loss of vision
    • Sudden loss of hearing
    • Ringing in the ears
    • Chest pain
    • Shortness of breath
    • Painful urination
    • Increased urination frequency
    • Fainting
    • Dizziness
    • Skin rash
    • Hives
    • Facial swelling

    If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

    As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

    Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

    In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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    This may be an opportunity to practice medicine safely. By taking this medication regularly, you can help prevent serious side effects. As with all prescription medications, inform your doctor of any medical conditions you used to get your hands on.

    As with all prescription medications, be sure to disclose all medical conditions you are related to this medication to your doctor so they can determine if it is necessary.

    As with all prescription medications, be sure to inform your doctor of any medical conditions you used to get your hands on.

    As with all prescription medications, be aware of any medical condition you are related to this medication to the health of your doctor.

    As with all prescription medications, be aware of any medical condition you used to get your hands on.

    As with all prescription medications, be aware of any medical condition you used to get your hands onto.

    As with all prescription medications, be aware of any medical condition you used to get onto auncide Cialis.